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019 a| 1374947748a| 1485293963;

020 a| 9783031150708q| electronic book;

020 a| 3031150708q| electronic book;

020 z| 9783031150692;

020 a| 3031150694;

020 a| 9783031150692;

024 7 a| 10.1007/978-3-031-15070-82| doi;

035 a| (OCoLC)1373986633z| (OCoLC)1374947748z| (OCoLC)1485293963;

050 4 a| QP379b| .E87 2023eb;

049 a| NEHH;

245 00 a| Essentials of cerebellum and cerebellar disorders :b| a primer for graduate students /c| Donna L. Gruol, Noriyuki Koibuchi, Mario Manto, Jeremy D. Schmahmann, Ying Shen, editors.;

250 a| Second edition.;

264 1 a| Cham, Switzerland :b| Springer,c| [2023];

300 a| 1 online resource (xiv, 742 pages : illustrations (some color)).;

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

347 a| text fileb| PDF2| rda;

504 a| Includes bibliographical references and index.;

520 a| This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. It is organized into easy to read and short chapters that are ideal for students and clinicians. The most common cerebellar disorders encountered in the clinic are covered. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from cerebellar laboratories and ataxia clinics throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar cellular biology and circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.;

588 a| Description based on online resource; title from digital title page (viewed on August 07, 2023).;

650 0 a| Cerebellum.;

650 0 a| Cerebellumx| Diseases.;

650 2 a| Cerebellum0| (DNLM)D002531;

650 2 a| Cerebellar Diseases0| (DNLM)D002526;

700 1 a| Gruol, Donna L.,e| editor.;

700 1 a| Koibuchi, Noriyuki,e| editor.;

700 1 a| Manto, Mario,e| editor.;

700 1 a| Molinari, Marco,e| editor.;

700 1 a| Schmahmann, Jeremy D.,e| editor.;

700 1 a| Shen, Ying,e| editor.;

758 i| has work:a| Essentials of cerebellum and cerebellar disorders (Text)1| https://id.oclc.org/worldcat/entity/E39PCGpJyjRxJCJWBP7pTHygXd4| https://id.oclc.org/worldcat/ontology/hasWork;

856 40 z| Direct link to eBooku| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=7217849;

880 0 6| 505-00/(Sa| Introduction -- Part I Brief Historical Note -- A Brief History of the Cerebellum -- Pivotal Insights: The Contributions of Gordon Holmes (1876-1965) and Olof Larsell (1886-1964) to Our Understanding of Cerebellar Function and Structure -- Part II Anatomy and Histology of the Cerebellum -- Gross Anatomy of the Cerebellum -- Vascular Supply and Territories of the Cerebellum -- The Olivocerebellar Tract -- Precerebellar Nuclei: Embryological Principles -- Vestibular Nuclei and Their Cerebellar Connections -- Spinocerebellar and Cerebellospinal Pathways -- Visual Circuits -- The Cerebrocerebellar System -- Cerebello-Cerebral Feedback Projections -- Part III Embryology and Development of the Cerebellum -- Cerebellar Neurogenesis -- Zones and Stripes -- Specification of Cerebellar Neurons -- Cerebellar Nucleus Development -- Development of Glutamatergic and GABAergic Synapses -- Synaptogenesis and Synapse Elimination in Developing Cerebellum -- Cerebellar Epigenetics: Transcription of microRNAs in Purkinje Neurons as an Approach to Neuronal Plasticity -- The Genetic Programs Behind Cerebellar Development -- Part IV Cerebellar Circuits: Biochemistry, Neurotransmitters and Neuromodulation -- Granule Cells and Parallel Fibers -- Purkinje Cells -- Stellate Cells -- Basket Cells -- Golgi Neurons -- Lugaro Cells -- Unipolar Brush Cells -- Glial Cells -- GABA Pathways and Receptors -- Glutamatergic Pathways and Receptors -- Norepinephrine in the Cerebellum -- Serotonin in the Cerebellum -- Nitric Oxide -- Cannabinoids -- Purinergic Signaling in the Cerebellum -- Neuropeptides in the Cerebellum -- Neuroactive Steroids -- Role of Unipolar Brush Cells in the Vestibulocerebellum -- Distributed Plasticity in the Cerebellar Circuit -- Part V Basic Physiology -- Simple Spikes and Complex Spikes -- Rebound Depolarizations -- Cerebellar Nuclei -- Plasticity of the Cerebellum -- Long-Term Depression at Parallel Fiber-Purkinje Cell Synapses -- Regulation of Calcium in the Cerebellum -- Neurotrophic Factors in Cerebellar Development and Function -- The Cerebellar Neuroimmune System -- Restoring a Loss of Mossy Fiber Plasticity in a Model of Fragile X Syndrome -- Part VI Neuroimaging of the Cerebellum -- Cerebellar Closed Loops -- MRI Aspects: Conventional, SWI, and DTI -- SPECT and PET -- MR Spectroscopy -- Functional Topography of the Human Cerebellum -- fMRI-Based Anatomy: Mapping the Cerebellum -- Part VII Functional Properties of the Cerebellum -- Cerebro-Cerebellar Networks -- Clinical Functional Topography in Cognition -- Sequencing -- Speech and Language -- Theory of Mind and Cerebellum -- Cerebellum and Decision-Making -- Part VIII Cellular and Animal Models of Cerebellar Disorders -- The Zebrafish Cerebellum -- The Teleost Fish -- Lurcher Mouse -- The Tottering Mouse -- The Rolling Nagoya Mouse -- Lesions of the Cerebellum -- The Staggerer Mouse: RORα Deficiency Induces Cerebellar Neurodegeneration -- Alcohol and the Cerebellum -- Moonwalker Mouse -- Part IX Human Cerebellar Symptoms: From Movement to Cognition -- Cerebellum and Oculomotor Deficits -- Speech Disorders -- Deficits of Limbs Movements -- The Three Cornerstones of the Cerebellar Syndrome -- Lesion-Symptom Mapping -- The Cerebellar Cognitive Affective Syndrome and the Neuropsychiatry of the Cerebellum -- Ataxia Scales for the Clinical Evaluation -- The Ataxic Gait -- The Social Cerebellum and Human Interactions -- Part X Human Cerebellar Disorders: From Prenatal Period to Elderly -- Genetics and Differential Diagnosis of Cerebellar Ataxias -- Overview of Ataxia in Childhood -- Cerebellar Pathology in Autism -- Cerebellar Pathology in Schizophrenia, Bipolar Disorder, and Major Depression -- Autosomal Recessive Ataxias -- X-Linked Ataxias -- Imaging of Malformations of the Hindbrain and Craniocervical Junction -- Cerebellar Stroke -- Immune-Mediated Cerebellar Ataxias -- Paraneoplastic Cerebellar Syndrome -- Essential Tremor -- Toxic Agents -- Endocrine Disorders -- Friedreich Ataxia -- Ataxia Telangiectasia -- Neuroimmune Mechanisms of Cerebellar Ataxias -- Primary Autoimmune Cerebellar Ataxia (PACA) -- Gluten Ataxia -- Cerebrotendinous Xanthomatosis -- Cerebellar Variant of Multiple System Atrophy (MSA-C) -- Cerebellar Tumors -- Post-traumatic Cerebellar Syndromes -- Superficial Siderosis -- Ataxia in Multiple Sclerosis -- CANVAS -- Spastic Paraplegia Type 7 (SPG7) -- Part XI Therapies of Cerebellar Ataxias -- Drugs in Selected Ataxias -- Cerebellar Stimulation -- Motor Rehabilitation of Cerebellar Disorders -- Editing the Genome -- Grafting -- Cerebellar Reserve.;

949 a| CLICK ON WEB ADDRESSw| ASISh| HSL102p| $330.020| HSLo| HMT;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER96o| HMT;

994 a| C0b| NEH;

596 a| 1 4;

998 a| 6728015;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6728015-1001l| HSLELECm| HSLp| $330.02r| Ys| Yt| HGENEBKu| 5/19/2026x| EBOOKz| HERESOURCE0| HSLo| .STAFF. HMT;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6728015-2001l| JNETm| JOYNERr| Ys| Yt| JNE3BKu| 5/19/2026x| EBOOKz| JERESOURCEo| .STAFF. HMT;

Essentials of cerebellum and cerebellar disorders : a primer for graduate students / Donna L. Gruol, Noriyuki Koibuchi, Mario Manto, Jeremy D. Schmahmann, Ying Shen, editors.

Format	Electronic
Edition	Second edition.
Publication	Cham, Switzerland : Springer, [2023]
Copyright Date	©2023
Description	1 online resource (xiv, 742 pages : illustrations (some color)).
Supplemental Content	Direct link to eBook
Subjects	Cerebellum. Cerebellum--Diseases. Cerebellum Cerebellar Diseases

Other author/creator	Gruol, Donna L., editor.
Other author/creator	Koibuchi, Noriyuki, editor.
Other author/creator	Manto, Mario, editor.
Other author/creator	Molinari, Marco, editor.
Other author/creator	Schmahmann, Jeremy D., editor.
Other author/creator	Shen, Ying, editor.
Abstract	This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. It is organized into easy to read and short chapters that are ideal for students and clinicians. The most common cerebellar disorders encountered in the clinic are covered. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from cerebellar laboratories and ataxia clinics throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar cellular biology and circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.
Bibliography note	Includes bibliographical references and index.
Source of description	Description based on online resource; title from digital title page (viewed on August 07, 2023).
Issued in other form	Print version: Gruol, Donna L. Essentials of Cerebellum and Cerebellar Disorders Cham : Springer International Publishing AG,c2023 9783031150692
ISBN	9783031150708 electronic book
ISBN	3031150708 electronic book
ISBN	3031150694
ISBN	9783031150692
Standard identifier#	10.1007/978-3-031-15070-8

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Essentials of cerebellum and cerebellar disorders : a primer for graduate students / Donna L. Gruol, Noriyuki Koibuchi, Mario Manto, Jeremy D. Schmahmann, Ying Shen, editors.

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